Homatropine Methylbromide ( NSC 34399 )

Catalog No. M16015 CAS No. 80-49-9

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Product Name

Homatropine Methylbromide
Note

Research use only, not for human use.
Brief Description

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics.
Description

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.
Synonyms

NSC 34399
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

mAChR (SHR-E); mAChR (WKY-E)
Research Area

Neurological Disease
Indication

——

CAS Number

80-49-9
Formula Weight

370.29
Molecular Formula

C17H24BrNO3
Purity

>98%(HPLC)
Solubility

Ethanol: 10 mg/mL (27.0 mM); Water: 74 mg/mL (199.84 mM); DMSO: 74 mg/mL (199.84 mM)
SMILES

C[N+]1(C2CCC1CC(C2)OC(=O)C(C3=CC=CC=C3)O)C.[Br-]
Chemical Name

(8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate;bromide

1.Bryant SM, et al. J Med Toxicol, 2006, 2(4), 156-159.

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